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  • Home
  • Daily Tasks
    • Dictations >
      • Circumcision
      • Cystoscopy >
        • Cysto-OR
        • Cysto, +/- RPG +/- stent >
          • Cysto w/ b/l RPG
          • Cysto, L RPG
          • Cysto, R RPG
          • Cysto, L stent w/o RPG
          • Cysto, L RPG, L Stent
          • Cysto, R Stent w/o RPG
          • Cysto, R RPG, R Stent
        • Cysto, bladder biopsy
        • Cysto and TRUS Prostate Biopsy (OR)
        • Cysto Botox (F)
        • Individual parts of cystos
      • Prostate Biopsy >
        • Cysto and TRUS Prostate Biopsy (OR)
        • TRUS Prostate Biopsy (OR)
        • TRUS Prostate Biopsy (office)
        • MRI Fusion TRUS Prostate Biopsy
      • Robot Left Radical Nephrectomy
      • Robot Right Radical Nephrectomy
      • Robot Radical Prostatectomy w/ PLND
      • TURBT (M)
      • Ureteroscopy >
        • L U-scope (flex), RPG, (F)
        • R U-scope (flex), RPG, (M)
        • L U-scope,semirigid laser, flex, RPG, stent removal, (F)
      • ESWL >
        • Left Proximal ESWL
        • Left Renal ESWL
        • Right Proximal ESWL
        • Right Renal ESWL
      • TURP
      • Vasectomy
    • Plans >
      • Erectile Dysfunction
      • NMIBC
      • Peyronie's Disease
      • Prostate Cancer
    • Medications >
      • Antibiotics >
        • Bactrim
        • Cephalosporins >
          • Keflex
        • Ciprofloxacin
        • Macrobid
        • Gentamicin
      • Medications and Dialysis
      • Anticoagulation and Antiplatelets
      • 5α-Reductase Inhibitors
      • PDE5i
      • Prostate Cancer Drugs >
        • Abiraterone
        • Androgen Receptor Blockers
        • Pembrolizumab
      • Anticholinergics & β-3 Agonists
      • Estrace
    • Patient Discussions >
      • Prostate Cancer
      • PSA Screening
      • Tobacco Cessation
    • Radiation Exposure
    • Medicolegal
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  • Subjects
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      • Neurogenic Bladder/Spinal Cord Injury
      • CKD/ESRD
      • Erectile Dysfunction >
        • IPP
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      • Overactive Bladder
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        • Imaging
        • Genomic Testing
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        • Prostate Biopsy
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        • Urine Markers
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        • Variant Histology
        • Trimodal Therapy
        • Post Cystectomy Care (ERAS)
        • Studies
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      • Ureteral Stenting
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      • Interstim & PTNS
      • Midurethral Sling
      • Sacrocolpopexy
    • Nephrectomy
    • PCNL
    • Prostate Biopsy
    • Radical Prostatectomy
    • Suprapubic Tube (SPT)
    • Urethral Catheters
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Cephalosporins

Please see linked detailed information for the common cephalosporins we use:
cephalexin (Keflex)
cefixime (Suprax)
ceftriaxone (Rocephine)

The following chart has links to wikipedia pages for various medications:
1st Generation
2nd Generation
Cefalexin (Keflex) (PO)
Cefazolin (Ancef)

​




Cefaclor (Ceclor)
Cefuroxime (Ceftin)
Antianaerobe activity:
Cefoxitin
Cefotetan (Cefotan)
Cefoxitin (Mefoxin)

​
Cefdinir (Omnicef)
Cefixime (Suprax)
Cefotaxime (Claforan)
Cefpodoxime (Vantin)
Ceftriaxone (Rocephin)
Antipseudomonal:
Ceftazidime (Fortaz)
Cefepime (Maxipime)

​





Ceftaroline

​






MSSA
Streptococci Grp A,B,C,G
Strep Viridans
S. pneumoniae
H. influenzae
E. coli
Klebsiella pneumoniae
Proteus mirabilis





​

​


Same as 1st Generation Plus:
​β-lactamase positive H. influenzae
Moraxella catarrhalis
Neisseria meningitidis
E. coli
Klebsiella pneumoniae
Proteus
Oral anaerobes
Cefoxitin & Cefotetan cover B. fragilis





Same as 1st Generation Plus:
Expanded gram-negative coverage
Oral anaerobes
S. aureus (OSSA)
Strep pneumoniae
Strep Grp A,B,C,G
Strep viridans
Gram negative rods
N. gonorrhea
All cover B. fragilis EXCEPT cefotaxime & ceftazidime
P. aeruginosa - ceftazidine only
Good gram-positive & gram-negative coverage
Anti-Pseudomonal (including ceftazidime resistant isolates)
Penetrates CSF
Limited anaerobic coverage







​
MRSA
gram-positive bacteria, activity of later-generation cephalosporins with broad-spectrum activity against gram-negative bacteria








​

​
Holes in coverage:
​No CNS Penetration
​Cefuroxime does not have good coverage of gut anaerobes

Cefoxitin or Cefotetan can be used as monotherapy of mild intra-abdominal & pelvic infections

Holes in coverage:
Poor gram-positive coverage

E. faecium
MRSA
All cover OSSA EXCEPT ceftazidime
Legionella / atypicals
Listeria
Acinetobacter
Not all cover Pseudomonas
lue
Picture
Picture
  1. Bartlett JG, Auwaerter PG, Pham PA (2010): The Johns Hopkins ABX Guide. Diagnosis and Treatment of Infectious Diseases. 2010 2nd Edition. Jones & Bartlett Publishers, Sudbury MA. (ISBN: 978-0-7637-8108-8)
  2. Deck DH, Winston LG (2012): Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics (Chapter 43). In: Basic and Clinical Pharmacology. 12e. Katzung BG, Masters SB, Trevor AJ (Editors). McGraw-Hill / Lange.
  3. rxlist.com (Cefazolin ®)

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  • Home
  • Daily Tasks
    • Dictations >
      • Circumcision
      • Cystoscopy >
        • Cysto-OR
        • Cysto, +/- RPG +/- stent >
          • Cysto w/ b/l RPG
          • Cysto, L RPG
          • Cysto, R RPG
          • Cysto, L stent w/o RPG
          • Cysto, L RPG, L Stent
          • Cysto, R Stent w/o RPG
          • Cysto, R RPG, R Stent
        • Cysto, bladder biopsy
        • Cysto and TRUS Prostate Biopsy (OR)
        • Cysto Botox (F)
        • Individual parts of cystos
      • Prostate Biopsy >
        • Cysto and TRUS Prostate Biopsy (OR)
        • TRUS Prostate Biopsy (OR)
        • TRUS Prostate Biopsy (office)
        • MRI Fusion TRUS Prostate Biopsy
      • Robot Left Radical Nephrectomy
      • Robot Right Radical Nephrectomy
      • Robot Radical Prostatectomy w/ PLND
      • TURBT (M)
      • Ureteroscopy >
        • L U-scope (flex), RPG, (F)
        • R U-scope (flex), RPG, (M)
        • L U-scope,semirigid laser, flex, RPG, stent removal, (F)
      • ESWL >
        • Left Proximal ESWL
        • Left Renal ESWL
        • Right Proximal ESWL
        • Right Renal ESWL
      • TURP
      • Vasectomy
    • Plans >
      • Erectile Dysfunction
      • NMIBC
      • Peyronie's Disease
      • Prostate Cancer
    • Medications >
      • Antibiotics >
        • Bactrim
        • Cephalosporins >
          • Keflex
        • Ciprofloxacin
        • Macrobid
        • Gentamicin
      • Medications and Dialysis
      • Anticoagulation and Antiplatelets
      • 5α-Reductase Inhibitors
      • PDE5i
      • Prostate Cancer Drugs >
        • Abiraterone
        • Androgen Receptor Blockers
        • Pembrolizumab
      • Anticholinergics & β-3 Agonists
      • Estrace
    • Patient Discussions >
      • Prostate Cancer
      • PSA Screening
      • Tobacco Cessation
    • Radiation Exposure
    • Medicolegal
    • Urology Jokes & Quotes
  • Subjects
    • Various Pathology >
      • Neurogenic Bladder/Spinal Cord Injury
      • CKD/ESRD
      • Erectile Dysfunction >
        • IPP
      • Female Urology
      • Hypogonadism
      • Imaging
      • Nocturia
      • Overactive Bladder
      • Trauma
      • Urine Retention
    • Urologic Malignancy >
      • Prostate Cancer >
        • Choosing Therapy
        • Imaging
        • Genomic Testing
        • Locally Advanced and BCR
        • Metastatic Prostate Cancer
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        • Surgery
        • Radiation
        • Adjuvant & Salvage Therapy
        • Prostate Biopsy
        • Studies >
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        • NMIBC >
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        • Urine Markers
        • Chemotherapy
        • Metastatic Bladder Cancer
        • Immunotherapy
        • Cystectomy & PLND
        • Variant Histology
        • Trimodal Therapy
        • Post Cystectomy Care (ERAS)
        • Studies
      • Renal Cancer >
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        • Treatment
        • Surgery
        • Renal Cysts
        • Locally Advanced & Metastatic
        • RCC Surveillance
        • Calculators & Nomograms
        • Landmark Studies
        • Other Studies
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        • UTUC Chemotherapy
        • Surgery
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      • Urolift
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      • Infertility in Spinal Cord Injury
      • Study guide
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      • Studies
    • Infection >
      • Fournier's Gangrene
      • Orchitis
      • UTI
      • Recurrent UTI
    • Incontinence >
      • Artificial Urethral Sphincter
      • Neuromodulation
      • Slings
      • Urethral Bulking
    • Pediatric Urology >
      • Pediatric Infections
      • Pediatric Surgery
      • Pediatric Tumors
      • Pediatric Trauma
    • Reconstruction >
      • Ureteral Stricture
      • Urethral Stricture
      • Studies
    • Other Random Studies >
      • Blood Transfusions
      • Fistula
      • Other studies/notes
  • Procedures
    • Cystectomy
    • Incisions
    • Endoscopic >
      • Cystoscopy
      • Ureteroscopy
      • Ureteral Stenting
    • Female Surgery >
      • Interstim & PTNS
      • Midurethral Sling
      • Sacrocolpopexy
    • Nephrectomy
    • PCNL
    • Prostate Biopsy
    • Radical Prostatectomy
    • Suprapubic Tube (SPT)
    • Urethral Catheters
    • Urodynamics
    • Varicocelectomy
  • Videos
  • Journal Club
    • Top 1000 Urology Journal Articles
    • Top Urology Journal Articles by Decade
    • Landmark Authors
    • Bladder Cancer Journal Club >
      • Landmark Papers
    • Reconstructive Journal Club >
      • Landmark Papers
    • Upper Tract Urothelial Carcinoma