Testicular Cancer: Landmark Studies
SEMPET - (127 patients) shows there may be a limited role for detection of residual disease in pure seminoma with sensitivity of 82%, specificity of 90%, NPV 95% and PPV 69% when performed 6 weeks after therapy. (1,2)
- Bachner, M., et al. "2-18fluoro-deoxy-D-glucose positron emission tomography (FDG-PET) for postchemotherapy seminoma residual lesions: a retrospective validation of the SEMPET trial." Annals of oncology 23.1 (2011): 59-64.
- De Santis, Maria, et al. "2-18fluoro-deoxy-D-glucose positron emission tomography is a reliable predictor for viable tumor in postchemotherapy seminoma: an update of the prospective multicentric SEMPET trial." Journal of Clinical Oncology 22.6 (2004): 1034-1039.