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Pediatric Infections

PEDS INFECTION
In the neonatal period males are two times more likely to have a UTI compared with females. From 1-6 months the incidence is approximately equal. From 6-12 months the ratio of UTIs in males to females is 1 to 4.
12-30% of children with a symptomatic UTI will have a recurrence.(
1,2,3,4,5) Renal scarring has been found in approximately 10% of children after first febrile UTI. (6) Data exists demonstrating that a 3-day course of methylprednisolone in conjunction with antibiotic therapy may reduce the occurrence and severity of renal scarring after acute pyelonephritis.44

  1. AUA Core Curriculum Pediatric Infections. Accessed 9/18/2018.
  2. Winberg, J., Andersen, H. J., Bergstrom, T. et al.: Epidemiology of symptomatic urinary tract infection in childhood. Acta Paediatr Scand Suppl: 1, 1974.
  3. Conway, P. H., Cnaan, A., Zaoutis, T. et al.: Recurrent urinary tract infections in children: risk factors and association with prophylactic antimicrobials. JAMA, 298: 179, 2007
  4. Panaretto, K., Craig, J., Knight, J. et al.: Risk factors for recurrent urinary tract infection in preschool children. J Paediatr Child Health, 35: 454, 1999.
  5. Williams, G. J., Wei, L., Lee, A. et al.: Long-term antibiotics for preventing recurrent urinary tract infection in children. Cochrane Database Syst Rev, 3: CD001534, 2011.
  6. Hoberman, A., Charron, M., Hickey, R. W. et al.: Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med, 348: 195, 2003.
  7. Huang, Y. Y., Chen, M. J., Chiu, N. T. et al.: Adjunctive oral methylprednisolone in pediatric acute pyelonephritis alleviates renal scarring. Pediatrics, 128: e496, 2011


























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