Estrace (Estrogen cream)
INDICATION
CONTRAINDICATIONS
1. Undiagnosed abnormal genital bleeding.
2. Known, suspected, or history of cancer of the breast.
3. Known or suspected estrogen-dependent neoplasia.
4. Active DVT, PE or history of these conditions.
5. Active arterial thromboembolic disease (for example, stroke, MI) or a history of these
conditions.
6. Known anaphylactic reaction or angioedema to ESTRACE (estradiol vaginal cream,USP, 0.01%).
7. Known liver dysfunction or disease.
8. Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
9. Known or suspected pregnancy.
DOSE
2 to 4 g (marked on the applicator) daily for one or two weeks, then gradually reduced to one half initial dosage for a similar period. A maintenance dosage of 1 g, one to three times a week, may be used after restoration of the vaginal mucosa has been achieved.
SIDE EFFECTS
CONTRAINDICATIONS
1. Undiagnosed abnormal genital bleeding.
2. Known, suspected, or history of cancer of the breast.
3. Known or suspected estrogen-dependent neoplasia.
4. Active DVT, PE or history of these conditions.
5. Active arterial thromboembolic disease (for example, stroke, MI) or a history of these
conditions.
6. Known anaphylactic reaction or angioedema to ESTRACE (estradiol vaginal cream,USP, 0.01%).
7. Known liver dysfunction or disease.
8. Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
9. Known or suspected pregnancy.
DOSE
2 to 4 g (marked on the applicator) daily for one or two weeks, then gradually reduced to one half initial dosage for a similar period. A maintenance dosage of 1 g, one to three times a week, may be used after restoration of the vaginal mucosa has been achieved.
SIDE EFFECTS
- Estrace package insert